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    Illustration of neural cells
    Licence-Ready

    Life SciencesPharma

    MPSIIIC Gene therapy for lysosomal storage disease

    Designed to address Mucopolysaccharidosis IIIC, this innovation presents a transformative solution for lysosomal storage diseases, spearheading advancements in genetic therapy
    Licence-Ready

    Health and BiotechLife Sciences

    One-pot enzymatic manufacturing of therapeutic oligonucleotides

    The scalable methodology revolutionising synthesis for disease-modulating sequences, shaping the future of therapeutic innovation.
    CGI illustration of a close-up view of a human brain scan, highlighting specific regions affected by Alzheimer's disease
    Investment-Ready

    Life SciencesPharma

    PharmaKure: Precision Medicines for Alzheimer’s and Parkinson’s Disease

    Pharmakure: Revolutionising Neurodegenerative Disease Treatment. Precision Medicines for Alzheimer's and Parkinson's
    wide angle shot of a vacuum system with people wearing full PPE using it

    Advanced MaterialsEngineering and Manufacturing

    2D Courier: Transporting 2D Materials into Semiconductor Manufacturing

    A vacuum-compatible, dry, adhesive-free process for pristine bonding & de-bonding of atomically thin films.
    Various syringes filled with colored liquids
    Licence-Ready

    Life SciencesPharma

    AbBind: A novel virus-like particle platform

    AbBind is an antibody compatible, plug-and-play virus-like particle platform with applications in vaccinology and tissue-specific gene therapy.

    Ruthenium close up

    Chemistry and PhysicsPhysical Sciences

    Ruthenium Catalysts

    Ruthenium Catalysts for Late Stage Functionalisation of Complex Molecules
    Steel sheets in warehouse

    Advanced MaterialsEngineering and Manufacturing

    High Performance Metal Organic Frameworks

    High surface area materials with the potential for gas storage, separation and catalysis

    Chemistry and Physics

    Bringing light to NMR spectroscopy

    In situ illumination of liquid-state samples makes it possible for a wide range of light-dependent chemical and biological phenomena to be studied by one of the most powerful analytical techniques - nuclear magnetic resonance (NMR) spectroscopy.
    Investment-Ready

    Energy and EnvironmentHealth and BiotechLife Sciences

    Plant Organelle Technologies

    Plant Organelle Technologies (POT), formerly EvoPlant, has developed a targeted technique which has the potential to improve photosynthesis, drought tolerance and herbicide resistance.
    Cedyr Labs Team

    A.I.ComputingElectricityEnergy and Environment

    Modular power management systems for smart electrification: Cedyr

    Cedyr are creating modular power systems for OEMs that make the smart electrification of products simple.
    Prof. Lydia Tabernero in the lab - Innovation Factory

    Health and BiotechLife SciencesPharma

    TaBriX- Innovative solutions for anti-infective therapies

    TaBriX - Developing innovative solutions to create anti-infectives for the future.
    Illustration of two elderly people made out of origami, smiling at each other
    Investment-Ready

    Life SciencesSoftware

    KOKU Health: Falls prevention for older adults

    KOKU Health Ltd. is a spinout from The University of Manchester, developing a digital platform for falls prevention and health literacy in older adults
    bipolar disorder mind mental health connection - Innovation Factory
    Investment-Ready

    MedtechSoftware

    CareLoop Health: Digital therapeutics for severe mental illness

    CareLoop Health Ltd. is a spinout from The University of Manchester using evidence-based software to predict problems, prevent escalation, and personalise care for individuals living with severe mental illness
    PVC pipes
    Close-up of plastic polymer granules with hands running through them.

    Chemistry and PhysicsEnergy and EnvironmentEngineering and Manufacturing

    Creating hard, tough and degradable polyester resins

    Plastic fantastic! A novel monomer family of cross linkers for the synthesis of high-performance, tough and degradable thermosetting polyester resins.

    Life Sciences

    Ravan Bio - Live longer and healthier

    Ravan Bio is identifing and re-purposing combinations of existing drugs and nutraceuticals to treat age-related conditions by targeting senescent cells.

    Life Sciences

    Identifying Genetic Biomarkers

    GeneGini enables Academic and Pharmaceutical Researchers to prognose, diagnose and sub-categorise more diseases with better accuracy and sensitivity.

    ComputingSoftware

    Crystal clear - CrystalGrower

    CrystalGrower is a tool to develop a greater understanding of how crystals grow at the nanoscale through simulation of crystal habit and surface topography that, in turn, helps predict and control functionality.

    The VEGA remotely operated vehicle (ROV) developed by The University of Manchester to access hard-to-reach spaces.

    ComputingElectronicsHardware

    University robotics technologies

    The University of Manchester are developing innovative robotic solutions to carry out inspections and maintenance underground, underwater, and in confined spaces.

    Life SciencesMedtech

    In the genes - Gene-cell therapies

    Duchenne Muscular Dystrophy can devastate a person’s life, resulting in mobility limitation and heart failure. Now, the latest in gene technology is being used to offer targeted therapies to patients in order to bring expertise to this vital area.
    X-rays of brains

    Life SciencesMedtechPharma

    Biotech brilliance - StrataStem Ltd

    StrataStem Ltd is a spinout biotechnology company seeking to transform the diagnosis and treatment of Alzheimer’s disease.

    MedtechSoftware

    Adept ADAPTations - ADAPT

    Even when a person has managed to beat cancer, it is an unfortunate fact that complications can arise years in the future due to the treatments they received for their cancer. There is therefore an urgent need to address this issue with measures to track and trace cancer treatment complications down the line.
    Covid-19, coronavirus | University of Manchester - Innovation Factory

    Chemistry and PhysicsHealth and BiotechPhysical Sciences

    Antiviral agents

    With the devastating effects of the Covid-19 pandemic still being felt around the globe, there is an ever-greater need for antiviral protection. Broad-spectrum antiviral agents have the potential to destroy a wide range of viruses and can be used in a wide variety of applications beyond drug modalities. This new platform technology is suitable for incorporation into antiviral coatings and could therefore transform the practice of sterilisation forever.

    Health and BiotechLife SciencesMedtech

    Dysphagia treatment - Phagenesis

    Invaluable treatment to transform the lives of patients who have difficulty swallowing.

    ComputingSoftware

    Whirlwind development - TornadoVM

    TornadoVM: A practical and efficient framework for accelerating managed programming languages on heterogeneous hardware accelerators

    Life SciencesPharma

    Spotting cell senescence - SenTraGor

    SenTraGor is an innovative, easy-to-use reagent for the reliable detection of Senescence in cells.

    Life SciencesPharma

    Stop bugging me! - Antimicrobial peptides

    Addressing concerns regarding super-resistant diseases which even the strongest medicines cannot touch, this peptide-packed technology is a remedy for the post-antibiotic age.
    abstract image of tendon

    Health and Biotech

    Fixing Achilles

    An innovative device designed to be delivered by keyhole surgery which specifically addresses the biology of a regenerating tendon to improve outcomes for patients.

    Advanced MaterialsEngineering and Manufacturing

    Still waters - Watercycle Technologies Ltd

    Watercycle Technologies have developed a high flux, low fouling membrane which, when coupled with its advanced membrane distillation (MD) technology, can treat highly concentrated wastewater from industries as diverse as desalination, mining, oil & gas, textiles, food & beverage, and others. The system has the additional advantage of having low running costs as the process is driven by thermal solar power or low grade waste heat from an industrial process.

    Life SciencesMedtech

    Stem cell super-test

    Testing stem cell health without testing stem cells! The great hope for future medical miracles has been made even easier with this breakthrough.
    VRGeoscience | University of Manchester - Innovation Factory

    ComputingEnergy and EnvironmentSoftware

    Going underground - VRGeoscience Ltd

    Spinout business VRGeoscience Ltd develop 3D technology to better understand deep underground structures.

    Life SciencesMedtech

    InPepCide - Fungal keratitis treatment

    Damage to the eye as a result of fungal infection remains a pressing issue, with early intervention not always being possible and long-term vision loss being common. This new technology can be the quick and accurate intervention needed to prevent permanent impairment.
    Professor Tariq Aslam and his son, Rafi, who inspired Rafi-Tone

    Life SciencesMedtechSoftware

    Breathe easy - Clin-e-cal Ltd

    Clin-e-cal is a spinout digital health company from The University of Manchester aiming to transform respiratory care.
    A 3D Rendering of a nerve structure on a white background.

    Life SciencesMedtech

    Touching a nerve - Polynerve

    Surgery to take nerves from one area of the body to replace those lost in another are a common solution for nerve injuries. However, these surgeries incur their own difficulties, such as loss of sensation and pain. Polynerve is a new device which will revolutionise the field of nerve repair.

    Life SciencesMedtechPharma

    Microbiology miracle – MicroBioSensor Ltd

    MicroBioSensor is a medical device company manufacturing point of care diagnostics for bacterial infections.

    Energy and EnvironmentEngineering and Manufacturing

    A virtuous circle - NovaCrack

    NovaCrack is a rapid depolymerisation process that transforms mixed plastic waste into high-value hydrocarbons which can be converted back to virgin polymers, thereby closing the loop for a truly circular economy.

    Life SciencesMedtechSoftware

    Dental development - Manchester Imaging Ltd

    Manchester Imaging Ltd is a successful spinout from The University of Manchester using software solutions to capture cavities and train the next generation of dentists.

    Life SciencesMedtech

    Rapid diagnosis for Parkinson’s - SebOMIX Ltd

    A non-invasive test for Parkinson’s Disease potentially offering rapid, non-invasive diagnosis before the onset of symptoms.
    Confocal Fluorescence Microscopy | University of Manchester - Innovation Factory
    Licence-Ready

    Life SciencesMedtech

    Super MAN stem cells - Ethical stem cells

    The procurement of stem cells, which are used in ever-more effective treatments for conditions such as Alzheimer’s disease, is a source of moral concern for many opposed to the practice. However, a new ethical solution may mitigate this flashpoint moral quandary.

    ManTRa Diagnostics

    Life SciencesMedtech

    Targeted cancer therapy - ManTRa Diagnostics

    ManTRa Diagnostics has developed tumour-site-specific gene expression signatures to assess hypoxia which has the potential to deliver major advances in personalised cancer medicine.

    Health and Biotech

    Light sight

    A light receptor with frequency-dependent activation level.

    Life SciencesMedtech

    The cellular level – eNAMPT stimulation

    A build-up of Nicotinamide Adenine Dinucleotide (NAD) in the body can result in the onset of various diseases and poor health outcomes. The University of Manchester have developed a new series of small molecule compounds, specifically designed to stimulate eNAMPT dimerization and have demonstrated these have potent activity leading to a corrective effect in in vitro and in vivo phenotypic models of diabetes. These could also have benefits in the treatment of a number of other diseases.

    ComputingElectronicsSoftware

    Pixel perfect - SCAMP vision sensor

    SCAMP is a low-power, high-speed machine vision device using cutting image sensors to execute a variety of vision algorithms.
    Licence-Ready

    Life SciencesMedtech

    A novel biologic for blood-clotting diseases

    caADAMTS13 is a preclinical-stage biologic therapy that dissolves blood clots in acute ischemic stroke. The therapy could also be used to treat other blood clotting diseases.

    Software

    The Future of Farming

    FOTENIX Ltd have developed a cutting-edge imaging system and analytical software to help growers and farmers improve crop yields, spot early signs of ripening and identify indications of disease or dehydration quick enough to take remedial action. This solution offers results far more reliable than the human eye and can be fully mobile enabling real time imaging and analysis to be carried out literally ‘in the field’.

    A.I.ComputingHardware

    Robotics for everyone - Puzzlebot

    Manchester Robotics have a mission to globalise access to learning and development tools for robotics. In doing so, they intend to close the £96bn/year STEM skills gap in the manufacturing workforce and democratise educational resources for society’s most disruptive technologies: robotics, automation and AI.

    Life SciencesPharma

    The missing link - Link Biologics

    Link Biologics is developing Link_TSG6, a protein biological, to treat common inflammatory and degenerative disorders of the ocular and musculoskeletal systems.
    Soldering robotics hardware

    ComputingHardware

    MONA robotic platform - Ice Nine Ltd

    Ice Nine Ltd is a spin-out business which specialises in innovative robotic solutions, in industries ranging from nuclear decommissioning to research and education.

    Advanced MaterialsEngineering and Manufacturing

    Improving elastomers - Grafine Ltd

    Grafine Ltd is the ground-breaking development and consultancy business that has a successful track record of maximising the performance of elastomers using a range of 2D materials, including grafine.

    infrared thermal imaging showing hand, and then showing the hand 'cloaked' by smartIR tile

    Advanced MaterialsEngineering and Manufacturing

    Invisibility cloak - SmartIR Ltd

    SmartIR’s innovative tiles have ability to control visible colour and infrared light creating limitless applications. Dynamic infrared patterns, thermal management solutions, and adaptive camouflage systems are just some the developments enabled by the manipulation of infrared light.

    A.I.ElectronicsHardwareSoftware

    Flexible thinking - Atomic Mechanics Ltd

    A completely new type of human machine interface (HMI) which is flexible, transparent and robust.
    Caspars Castle digital game

    Life SciencesSoftware

    Vision quest - Caspar's Castle

    Testing the visual field of children is difficult, resulting in inaccurate and unreliable outcomes which can lead to sight loss and other conditions. The University of Manchester has hopes to change that with novel software which is quite the spectacle.

    ComputingMedtechSoftware

    Digital doctors - Sentira

    With cutting-edge technology as sharp as a scalpel, Sentra has the means to train a new generation of healthcare professionals with virtual reality, using simulated surgeons, pretend patients, and all manner of virtual organs to get results.
    Illustration of eye | University of Manchester - Innovation Factory

    Health and Biotech

    A vision of success - Complement Therapeutics Ltd

    Taking on two devastating immune system diseases, AMD and GA, Complement Therapeutics Ltd is developing new strategies to enhance one of the most promising areas in patient care.