CGI illustration of a close-up view of a human brain scan, highlighting specific regions affected by Alzheimer's disease

Life SciencesPharma

PharmaKure: Precision Medicines for Alzheimer’s and Parkinson’s Disease

Pharmakure: Revolutionising Neurodegenerative Disease Treatment. Precision Medicines for Alzheimer's and Parkinson's
wide angle shot of a vacuum system with people wearing full PPE using it

Advanced MaterialsEngineering and Manufacturing

2D Courier: Transporting 2D Materials into Semiconductor Manufacturing

A vacuum-compatible, dry, adhesive-free process for pristine bonding & de-bonding of atomically thin films.
Various syringes filled with colored liquids

Life SciencesPharma

AbBind: A novel virus-like particle platform

AbBind is an antibody compatible, plug-and-play virus-like particle platform with applications in vaccinology and tissue-specific gene therapy.

Ruthenium close up

Chemistry and PhysicsPhysical Sciences

Ruthenium Catalysts for Late Stage Functionalisation of Complex Molecules
Steel sheets in warehouse

Advanced MaterialsEngineering and Manufacturing

High Performance Metal Organic Frameworks

High surface area materials with the potential for gas storage, separation and catalysis

Chemistry and Physics

Bringing light to NMR spectroscopy

In situ illumination of liquid-state samples makes it possible for a wide range of light-dependent chemical and biological phenomena to be studied by one of the most powerful analytical techniques - nuclear magnetic resonance (NMR) spectroscopy.

Energy and EnvironmentHealth and BiotechLife Sciences

Chlomita Ltd: A rapid transgene-free technology used to improve plant traits

Chlomita Ltd (Formerly EvoPlant), develops targeted technique which has the potential to improve photosynthesis, drought tolerance and herbicide resistance.
Cedyr Labs Team

Electricity

Modular power management systems for smart electrification: Cedyr Labs

Cedyr Labs is creating modular power systems for OEMs that make the smart electrification of products simple.
Prof. Lydia Tabernero in the lab - Innovation Factory

Health and BiotechLife SciencesPharma

TaBriX- Innovative solutions for anti-infective therapies

TaBriX - Developing innovative solutions to create anti-infectives for the future.
Illustration of two elderly people made out of origami, smiling at each other

Life SciencesSoftware

KOKU Health: Falls prevention for older adults

KOKU Health Ltd. is a spinout from The University of Manchester, developing a digital platform for falls prevention and health literacy in older adults
bipolar disorder mind mental health connection - Innovation Factory

MedtechSoftware

CareLoop Health: Digital therapeutics for severe mental illness

CareLoop Health Ltd. is a spinout from The University of Manchester using evidence-based software to predict problems, prevent escalation, and personalise care for individuals living with severe mental illness
PVC pipes
Close-up of plastic polymer granules with hands running through them.

Chemistry and PhysicsEnergy and EnvironmentEngineering and Manufacturing

Creating hard, tough and degradable polyester resins

Plastic fantastic! A novel monomer family of cross linkers for the synthesis of high-performance, tough and degradable thermosetting polyester resins.

Life Sciences

Ravan Bio - Live longer and healthier

Ravan Bio is identifing and re-purposing combinations of existing drugs and nutraceuticals to treat age-related conditions by targeting senescent cells.

Energy and Environment

Quantifying recycled content in plastics and packaging – ReCon2

The use and disposal of synthetic polymers in packaging and other applications has become a critical environmental issue, and one that we must control as a society.

Life Sciences

Identifying Genetic Biomarkers

GeneGini enables Academic and Pharmaceutical Researchers to prognose, diagnose and sub-categorise more diseases with better accuracy and sensitivity.

ComputingSoftware

Crystal clear - CrystalGrower

CrystalGrower is a tool to develop a greater understanding of how crystals grow at the nanoscale through simulation of crystal habit and surface topography that, in turn, helps predict and control functionality.

The VEGA remotely operated vehicle (ROV) developed by The University of Manchester to access hard-to-reach spaces.

ComputingElectronicsHardware

University robotics technologies

The University of Manchester are developing innovative robotic solutions to carry out inspections and maintenance underground, underwater, and in confined spaces.

Life SciencesMedtech

In the genes - Gene-cell therapies

Duchenne Muscular Dystrophy can devastate a person’s life, resulting in mobility limitation and heart failure. Now, the latest in gene technology is being used to offer targeted therapies to patients in order to bring expertise to this vital area.
X-rays of brains

Life SciencesMedtechPharma

Biotech brilliance - StrataStem Ltd

StrataStem Ltd is a spinout biotechnology company seeking to transform the diagnosis and treatment of Alzheimer’s disease.

MedtechSoftware

Adept ADAPTations - ADAPT

Even when a person has managed to beat cancer, it is an unfortunate fact that complications can arise years in the future due to the treatments they received for their cancer. There is therefore an urgent need to address this issue with measures to track and trace cancer treatment complications down the line.
Covid-19, coronavirus | University of Manchester - Innovation Factory

Chemistry and PhysicsHealth and BiotechPhysical Sciences

Antiviral agents

With the devastating effects of the Covid-19 pandemic still being felt around the globe, there is an ever-greater need for antiviral protection. Broad-spectrum antiviral agents have the potential to destroy a wide range of viruses and can be used in a wide variety of applications beyond drug modalities. This new platform technology is suitable for incorporation into antiviral coatings and could therefore transform the practice of sterilisation forever.

Health and BiotechLife SciencesMedtech

Dysphagia treatment - Phagenesis

Invaluable treatment to transform the lives of patients who have difficulty swallowing.

ComputingSoftware

Whirlwind development - TornadoVM

TornadoVM: A practical and efficient framework for accelerating managed programming languages on heterogeneous hardware accelerators

Life SciencesPharma

Spotting cell senescence - SenTraGor

SenTraGor is an innovative, easy-to-use reagent for the reliable detection of Senescence in cells.

Life SciencesPharma

Stop bugging me! - Antimicrobial peptides

Addressing concerns regarding super-resistant diseases which even the strongest medicines cannot touch, this peptide-packed technology is a remedy for the post-antibiotic age.
abstract image of tendon

Health and Biotech

Fixing Achilles

An innovative device designed to be delivered by keyhole surgery which specifically addresses the biology of a regenerating tendon to improve outcomes for patients.

Advanced MaterialsEngineering and Manufacturing

Still waters - Watercycle Technologies Ltd

Watercycle Technologies have developed a high flux, low fouling membrane which, when coupled with its advanced membrane distillation (MD) technology, can treat highly concentrated wastewater from industries as diverse as desalination, mining, oil & gas, textiles, food & beverage, and others. The system has the additional advantage of having low running costs as the process is driven by thermal solar power or low grade waste heat from an industrial process.

Life SciencesMedtech

Stem cell super-test

Testing stem cell health without testing stem cells! The great hope for future medical miracles has been made even easier with this breakthrough.
VRGeoscience | University of Manchester - Innovation Factory

ComputingEnergy and EnvironmentSoftware

Going underground - VRGeoscience Ltd

Spinout business VRGeoscience Ltd develop 3D technology to better understand deep underground structures.

Life SciencesMedtech

InPepCide - Fungal keratitis treatment

Damage to the eye as a result of fungal infection remains a pressing issue, with early intervention not always being possible and long-term vision loss being common. This new technology can be the quick and accurate intervention needed to prevent permanent impairment.
Professor Tariq Aslam and his son, Rafi, who inspired Rafi-Tone

Life SciencesMedtechSoftware

Breathe easy - Clin-e-cal Ltd

Clin-e-cal is a spinout digital health company from The University of Manchester aiming to transform respiratory care.

ComputingSoftware

Enhancing the Visual Experience of AR & VR

With an upgrade on the industry-standard trichromatic colour space, The University of Manchester have revised colour mapping to improve image quality and transform the palette of visual image creation.
A 3D Rendering of a nerve structure on a white background.

Life SciencesMedtech

Touching a nerve - Polynerve

Surgery to take nerves from one area of the body to replace those lost in another are a common solution for nerve injuries. However, these surgeries incur their own difficulties, such as loss of sensation and pain. Polynerve is a new device which will revolutionise the field of nerve repair.

Life SciencesMedtechPharma

Microbiology miracle – MicroBioSensor Ltd

MicroBioSensor is a medical device company manufacturing point of care diagnostics for bacterial infections.

Energy and EnvironmentEngineering and Manufacturing

A virtuous circle - NovaCrack

NovaCrack is a rapid depolymerisation process that transforms mixed plastic waste into high-value hydrocarbons which can be converted back to virgin polymers, thereby closing the loop for a truly circular economy.

Life SciencesMedtechSoftware

Dental development - Manchester Imaging Ltd

Manchester Imaging Ltd is a successful spinout from The University of Manchester using software solutions to capture cavities and train the next generation of dentists.

Life SciencesMedtech

Rapid diagnosis for Parkinson’s - SebOMIX Ltd

A non-invasive test for Parkinson’s Disease potentially offering rapid, non-invasive diagnosis before the onset of symptoms.
Confocal Fluorescence Microscopy | University of Manchester - Innovation Factory

Life SciencesMedtech

Super MAN stem cells - Ethical stem cells

The procurement of stem cells, which are used in ever-more effective treatments for conditions such as Alzheimer’s disease, is a source of moral concern for many opposed to the practice. However, a new ethical solution may mitigate this flashpoint moral quandary.

ManTRa Diagnostics

Life SciencesMedtech

Targeted cancer therapy - ManTRa Diagnostics

ManTRa Diagnostics has developed tumour-site-specific gene expression signatures to assess hypoxia which has the potential to deliver major advances in personalised cancer medicine.

Health and Biotech

Light sight

A light receptor with frequency-dependent activation level.

Life SciencesMedtech

The cellular level – eNAMPT stimulation

A build-up of Nicotinamide Adenine Dinucleotide (NAD) in the body can result in the onset of various diseases and poor health outcomes. The University of Manchester have developed a new series of small molecule compounds, specifically designed to stimulate eNAMPT dimerization and have demonstrated these have potent activity leading to a corrective effect in in vitro and in vivo phenotypic models of diabetes. These could also have benefits in the treatment of a number of other diseases.

ComputingElectronicsSoftware

Pixel perfect - SCAMP vision sensor

SCAMP is a low-power, high-speed machine vision device using cutting image sensors to execute a variety of vision algorithms.

Life SciencesMedtech

A novel biologic for blood-clotting diseases

caADAMTS13 is a preclinical-stage biologic therapy that dissolves blood clots in acute ischemic stroke. The therapy could also be used to treat other blood clotting diseases.

Software

The future of farming – FOTENIX Ltd

FOTENIX Ltd have developed a cutting-edge imaging system and analytical software to help growers and farmers improve crop yields, spot early signs of ripening and identify indications of disease or dehydration quick enough to take remedial action. This solution offers results far more reliable than the human eye and can be fully mobile enabling real time imaging and analysis to be carried out literally ‘in the field’.

A.I.ComputingHardware

Robotics for everyone - Puzzlebot

Manchester Robotics have a mission to globalise access to learning and development tools for robotics. In doing so, they intend to close the £96bn/year STEM skills gap in the manufacturing workforce and democratise educational resources for society’s most disruptive technologies: robotics, automation and AI.

Life SciencesPharma

The missing link - Link Biologics

Link Biologics is developing Link_TSG6, a protein biological, to treat common inflammatory and degenerative disorders of the ocular and musculoskeletal systems.
Soldering robotics hardware

ComputingHardware

MONA robotic platform - Ice Nine Ltd

Ice Nine Ltd is a spin-out business which specialises in innovative robotic solutions, in industries ranging from nuclear decommissioning to research and education.

Advanced MaterialsEngineering and Manufacturing

Improving elastomers - Grafine Ltd

Grafine Ltd is the ground-breaking development and consultancy business that has a successful track record of maximising the performance of elastomers using a range of 2D materials, including grafine.

infrared thermal imaging showing hand, and then showing the hand 'cloaked' by smartIR tile

Advanced MaterialsEngineering and Manufacturing

Invisibility cloak - SmartIR Ltd

SmartIR’s innovative tiles have ability to control visible colour and infrared light creating limitless applications. Dynamic infrared patterns, thermal management solutions, and adaptive camouflage systems are just some the developments enabled by the manipulation of infrared light.

A.I.ElectronicsHardwareSoftware

Flexible thinking - Atomic Mechanics Ltd

A completely new type of human machine interface (HMI) which is flexible, transparent and robust.
Caspars Castle digital game

Life SciencesSoftware

Vision quest - Caspar's Castle

Testing the visual field of children is difficult, resulting in inaccurate and unreliable outcomes which can lead to sight loss and other conditions. The University of Manchester has hopes to change that with novel software which is quite the spectacle.

ComputingMedtechSoftware

Digital doctors - Sentira

With cutting-edge technology as sharp as a scalpel, Sentra has the means to train a new generation of healthcare professionals with virtual reality, using simulated surgeons, pretend patients, and all manner of virtual organs to get results.
Illustration of eye | University of Manchester - Innovation Factory

Health and Biotech

A vision of success - Complement Therapeutics Ltd

Taking on two devastating immune system diseases, AMD and GA, Complement Therapeutics Ltd is developing new strategies to enhance one of the most promising areas in patient care.